Blood Group O Rh-negative in Obstetrics & Gynecology — Case | General Gynecology | SMLE Q#404
SMLE Question #404
Obstetrics & Gynecology
General Gynecology
Last updated: February 2026
A 26-year-old primigravida with blood group O Rh-negative delivers a healthy term male infant via spontaneous vaginal delivery. The infant’s cord blood is O Rh-positive with a negative direct antiglobulin (Coombs) test. The delivery is uncomplicated, and she has no history of transfusion, abortion, or previous pregnancy. What is the most appropriate management to prevent Rh isoimmunization in this mother?
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