Only Partial Improvement in Medicine / Internal Medicine — 35yo Man | Gastroenterology | SMLE Q#320

SMLE Question #320

Medicine / Internal Medicine Gastroenterology
Last updated: February 2026
A 35-year-old man has 1 year of heartburn and regurgitation after meals and when lying down. He has no dysphagia, weight loss, gastrointestinal bleeding, or anemia. He took esomeprazole 20 mg once daily for 8 weeks, 30 minutes before breakfast, with only partial improvement. His BMI is 29 kg/m². What is the most appropriate next step in management?

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