Levothyroxine 75 Micrograms Daily in Obstetrics & Gynecology — 29yo Woman | General Gynecology | SMLE Q#302

SMLE Question #302

Obstetrics & Gynecology General Gynecology
Last updated: February 2026
A 29-year-old woman, G1P0, at 8 weeks of gestation presents for her first antenatal visit. She has primary hypothyroidism treated with levothyroxine 75 micrograms daily and was euthyroid on testing 3 months before conception. She reports mild fatigue but no palpitations, tremor, or heat intolerance. Physical examination is unremarkable, and ultrasound confirms a viable intrauterine pregnancy. What is the most appropriate adjustment of her levothyroxine therapy at this visit?

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