Sour Taste in Medicine / Internal Medicine — 45yo Man | Gastroenterology | SMLE Q#286

SMLE Question #286

Medicine / Internal Medicine Gastroenterology
Last updated: February 2026
A 45-year-old man has 3 weeks of recurrent burning retrosternal discomfort with sour taste and regurgitation after large meals and when lying down. He had similar symptoms 1 year ago that resolved on omeprazole 40 mg once daily, but he stopped it 4 months ago. He denies dysphagia, odynophagia, gastrointestinal bleeding, unintentional weight loss, persistent vomiting, or anemia symptoms. What is the most appropriate next step in management?

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