Prematurity-related Lung Disease in Pediatrics — Case | Pediatric Respiratory | SMLE Q#18480

SMLE Question #18480

Pediatrics Pediatric Respiratory

Objective: OBJ-RESP-NEO-001

Last updated: February 2026
A 3-month-old girl (corrected age 1 month) born at 28 weeks’ gestation required endotracheal ventilation early in the NICU course, followed by noninvasive positive-pressure support for prematurity-related lung disease. She is now off respiratory support and feeding orally. She develops a persistent expiratory (monophasic) wheeze that is most noticeable during feeding and agitation. She has no fever, cough, or increased work of breathing, and a chest radiograph shows no focal infiltrate. What is the most likely diagnosis?

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