Newly Diagnosed Hypertension in Medicine / Internal Medicine — 55yo Man | Rheumatology | SMLE Q#18404

SMLE Question #18404

Medicine / Internal Medicine Rheumatology

Objective: OBJ-IM-RHEUM-215

Last updated: February 2026
A 55-year-old man with newly diagnosed hypertension and type 2 diabetes mellitus is started on several new medications. Three days later, he develops sudden severe pain with erythema, warmth, and swelling of the first metatarsophalangeal joint and cannot tolerate light touch from bedsheets. He has no trauma and no fever. Which medication is most likely responsible for this adverse effect?

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