3 Weeks Of Burning in Medicine / Internal Medicine — 34yo Woman | Gastroenterology | SMLE Q#18189

SMLE Question #18189

Medicine / Internal Medicine Gastroenterology

Objective: OBJ-PEP-001

A 34-year-old woman presents to clinic with 3 weeks of burning epigastric pain that worsens 1–2 hours after eating and sometimes wakes her at night. She has been taking ibuprofen 600 mg three times daily for chronic knee pain for several months. She denies hematemesis, melena, syncope, or unintentional weight loss. Upper endoscopy shows a 1.0 cm clean-based ulcer in the first part of the duodenum without active bleeding. Biopsy/rapid urease testing is positive for Helicobacter pylori. What is the next step in management?

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