Asthma To Emergency Department in Medicine / Internal Medicine — 28yo Man | Respiratory / Pulmonology | SMLE Q#17906

SMLE Question #17906

Medicine / Internal Medicine Respiratory / Pulmonology

Objective: OBJ-RESP-ACUTE-VENT-001

Last updated: February 2026
A 28-year-old man with asthma presents to the emergency department with severe dyspnoea and bilateral wheeze. He receives high-flow oxygen and repeated nebulised salbutamol. After 1 hour, he becomes drowsy and less responsive. Arterial blood gas on oxygen is obtained. What is the most appropriate initial step in management?

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