Systemic Lupus Erythematosus Is in Medicine / Internal Medicine — 34yo Woman | Rheumatology | SMLE Q#17870

SMLE Question #17870

Medicine / Internal Medicine Rheumatology

Objective: OBJ-383

Last updated: February 2026
A 34-year-old woman with systemic lupus erythematosus is on hydroxychloroquine and attends routine follow-up. She feels well with no edema, hematuria, foamy urine, or reduced urine output. Examination shows no peripheral edema. A kidney biopsy performed for previous concern about renal involvement is reported as class I (minimal mesangial) lupus nephritis. What is the most appropriate initial management?

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