Play in Pediatrics — Case | Pediatric Heme/Onc | SMLE Q#17771

SMLE Question #17771

Pediatrics Pediatric Heme/Onc

Objective: OBJ-153

Last updated: February 2026
An 18-month-old child has 2 months of progressive pallor, easy fatigability, and intermittent shortness of breath with play. Parents report two prior episodes of painful swelling of the hands and feet. Examination shows pallor, mild scleral icterus, and a soft systolic flow murmur. A hemoglobinopathy with chronic hemolysis and episodic vaso-occlusion is suspected. What is the confirmatory diagnostic test?

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