28-year-old Woman in Medicine / Internal Medicine — 28yo Woman | Gastroenterology | SMLE Q#17648

SMLE Question #17648

Medicine / Internal Medicine Gastroenterology

Objective: OBJ-433

Last updated: February 2026
A 28-year-old woman has 8 months of chronic non-bloody diarrhea, abdominal bloating, and unintentional weight loss. She reports fatigue and recurrent mouth ulcers. She has no recent travel or sick contacts and continues a gluten-containing diet. Examination shows mild pallor and a pruritic, grouped vesicular rash on both elbow extensor surfaces. Which of the following is the best initial test to confirm suspected celiac disease?

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