Rheumatoid Arthritis Diagnosed 6 in Medicine / Internal Medicine — 35yo Man | Rheumatology | SMLE Q#17429

SMLE Question #17429

Medicine / Internal Medicine Rheumatology

Objective: OBJ-RA-ESCALATE-001

Last updated: February 2026
A 35-year-old man with rheumatoid arthritis diagnosed 6 months ago has worsening pain and swelling in both hands and feet with morning stiffness for 2 hours despite methotrexate 20 mg weekly and daily ibuprofen. Examination shows synovitis and tenderness of both wrists and several MCP joints. Hand X-rays show erosions at multiple joints. What is the most appropriate additional treatment?

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