12 Hours Of Fever in Pediatrics — 11yo Child | Pediatric Heme/Onc | SMLE Q#17261

SMLE Question #17261

Pediatrics Pediatric Heme/Onc

Objective: OBJ-153

Last updated: February 2026
An 11-year-old boy with homozygous sickle cell disease presents with 12 hours of fever, sharp left-sided pleuritic chest pain, and worsening shortness of breath. He is uncomfortable with decreased breath sounds and fine crackles at both lung bases. Chest radiograph shows new bilateral patchy infiltrates compared with a film from 1 month ago. What is the most likely diagnosis?

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