Iron Deficiency in Medicine / Internal Medicine — 27yo Woman | Gastroenterology | SMLE Q#16998

SMLE Question #16998

Medicine / Internal Medicine Gastroenterology

Objective: OBJ-433

Last updated: February 2026
A 27-year-old woman has 6 months of chronic diarrhea, abdominal bloating, and 5-kg unintentional weight loss. She reports fatigue and has microcytic anemia consistent with iron deficiency. Celiac serology shows positive IgA tissue transglutaminase and endomysial antibodies while she continues a gluten-containing diet. She has not started any dietary restrictions. What is the most appropriate next step to confirm the diagnosis of celiac disease?

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