Seropositive Erosive Rheumatoid Arthritis in Medicine / Internal Medicine — 48yo Woman | Rheumatology | SMLE Q#16834
SMLE Question #16834
Medicine / Internal Medicine
Rheumatology
Objective: OBJ-383
Last updated: February 2026
A 48-year-old woman with seropositive erosive rheumatoid arthritis has persistent painful swollen MCP and wrist joints and morning stiffness for 2 months. She has been adherent to methotrexate 15 mg weekly with folic acid and prednisolone 5 mg daily for 6 months. She has no fever or focal infection symptoms. Inflammatory markers remain elevated. What is the most appropriate next step in management?
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