Photosensitive Malar Rash Sparing in Medicine / Internal Medicine — 22yo Woman | Rheumatology | SMLE Q#16803

SMLE Question #16803

Medicine / Internal Medicine Rheumatology

Objective: OBJ-383

Last updated: February 2026
A 22-year-old woman presents with a photosensitive malar rash sparing the nasolabial folds, painless oral ulcers, and symmetric polyarthritis. Laboratory testing shows pancytopenia, low complement levels, and an elevated ESR with a normal CRP. Which antibody test is most appropriate to confirm the diagnosis of systemic lupus erythematosus?

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