12 Hours Of Sudden-onset in Medicine / Internal Medicine — 47yo Man | Rheumatology | SMLE Q#16798

SMLE Question #16798

Medicine / Internal Medicine Rheumatology

Objective: OBJ-383

Last updated: February 2026
A 47-year-old man presents to the emergency department with 12 hours of sudden-onset severe pain and swelling of the right first metatarsophalangeal joint, beginning overnight. He cannot tolerate light touch over the joint. He denies recent trauma, preceding illness, urethral discharge, or rash. Examination shows an erythematous, warm, markedly tender, swollen first MTP joint with limited range of motion; other joints are normal. What is the most likely cause of this presentation?

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