Morning Periorbital Puffiness in Pediatrics — 6yo Child | Pediatric Nephrology | SMLE Q#16424

SMLE Question #16424

Pediatrics Pediatric Nephrology

Objective: OBJ-436

Last updated: February 2026
A 6-year-old boy has 3 weeks of progressive swelling with morning periorbital puffiness, increasing leg and lower back swelling, and mild abdominal distension. Examination shows periorbital puffiness, sacral edema, and bilateral pitting lower-extremity edema. He has no shortness of breath and his urine is not discolored. Which of the following is the most likely diagnosis?

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