Known Homozygous Sickle Cell in Pediatrics — 2yo Child | Pediatric Heme/Onc | SMLE Q#16415
SMLE Question #16415
Pediatrics
Pediatric Heme/Onc
Objective: OBJ-153
Last updated: February 2026
A 2-year-old boy with known homozygous sickle cell disease is brought to the emergency department for painful swelling of both hands and feet for 1 day. There is no history of trauma, insect bites, or skin wounds. He is irritable and refuses to grasp toys. Examination shows symmetric swelling of the hands and feet that is warm and tender, without fluctuance, erythematous streaking, or focal joint limitation. Which of the following is the most likely diagnosis?
Continue in practice mode
Sign in and start a focused practice session to view options, submit your answer, and read the full explanation.