Vaginal Spotting in Obstetrics & Gynecology — Case | General Gynecology | SMLE Q#1614

SMLE Question #1614

Obstetrics & Gynecology General Gynecology

Objective: OBJ-ETH-STERIL

Last updated: February 2026
A 19-year-old primigravida at 10 weeks’ amenorrhea presents with vaginal spotting and severe nausea/vomiting with poor oral intake. She reports passing tissue per vaginam. Pelvic examination shows a uterus larger than expected for gestational age, and fetal heart tones are not detected. Transvaginal ultrasound shows an enlarged uterine cavity filled with heterogeneous echogenic material with multiple small cystic spaces, without an identifiable embryo or gestational sac. What is the most likely diagnosis?

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