Negative Margins in Medicine / Internal Medicine — 47yo Woman | Endocrinology | SMLE Q#1271

SMLE Question #1271

Medicine / Internal Medicine Endocrinology
Last updated: February 2026
A 47-year-old woman underwent uncomplicated total thyroidectomy for a 1.8-cm papillary thyroid carcinoma confined to the thyroid with negative margins and no lymphovascular invasion or metastases. She is taking levothyroxine and is clinically well at her 6-week postoperative visit. The surgeon plans long-term surveillance for recurrent or persistent differentiated thyroid cancer after surgery. Which of the following is the most appropriate primary laboratory test for surveillance in this patient?

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