Normal Overlying Skin in Surgery — 45yo Man | General Surgery | SMLE Q#12453

SMLE Question #12453

Surgery General Surgery

Objective: OBJ-TRACH-EMERG-01

Last updated: February 2026
A 45-year-old man has a painless, progressively enlarging posterior right upper-arm mass for 3 months, now limiting movement. Examination shows a 6-cm deep mass fixed to underlying tissues with normal overlying skin. MRI shows a heterogeneous deep soft-tissue mass with irregular margins and central necrosis. What is the most appropriate next investigation to confirm the diagnosis and obtain adequate tissue for histopathological evaluation?

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