Definitive Fetal Chromosomal Analysis in Obstetrics & Gynecology — Case | General Gynecology | SMLE Q#12448

SMLE Question #12448

Obstetrics & Gynecology General Gynecology

Objective: OBJ-ETH-STERIL

Last updated: February 2026
A 32-year-old primigravida at 17 weeks’ gestation attends routine prenatal care. First-trimester combined screening indicates increased risk of trisomy 21. Detailed ultrasound shows no structural fetal anomalies. Which specimen is most appropriate for definitive fetal chromosomal analysis at this gestational age?

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