Lifelong Medication in Medicine / Internal Medicine — 28yo Woman | Endocrinology | SMLE Q#12379
SMLE Question #12379
Medicine / Internal Medicine
Endocrinology
Objective: OBJ-ADDISON-DOSE-1
Last updated: February 2026
A 28-year-old woman has 4 months of progressive fatigue, sleepiness, constipation, mental slowing, and 6-kg weight gain. Her mother has thyroid disease treated with lifelong medication. Examination shows dry, cool skin, mild periorbital puffiness, delayed relaxation of deep tendon reflexes, and a diffusely firm, mildly enlarged, nontender thyroid. What is the most likely diagnosis?
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