Graves Disease Has Been in Medicine / Internal Medicine — 32yo Woman | Endocrinology | SMLE Q#1237

SMLE Question #1237

Medicine / Internal Medicine Endocrinology
Last updated: February 2026
A 32-year-old woman with Graves disease has been taking carbimazole for 10 months with good adherence but still has palpitations, heat intolerance, weight loss, and anxiety. Examination shows a fine tremor and a diffuse, non-tender goiter without nodules; there is no ophthalmopathy. She is not pregnant and is not planning pregnancy. Thyroid function tests remain abnormal. What is the most appropriate next step in management?

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