1 Month Of Polyuria in Medicine / Internal Medicine — Case | Endocrinology | SMLE Q#12349
SMLE Question #12349
Medicine / Internal Medicine
Endocrinology
Objective: OBJ-ADDISON-DOSE-1
Last updated: February 2026
A 17-year-old previously healthy boy presents with 1 month of polyuria, polydipsia, and weight loss, and 12 hours of diffuse abdominal pain and progressive drowsiness. He is ill-appearing and dehydrated with deep Kussmaul respirations. Urinalysis is positive for glucose and ketones, and ECG shows sinus tachycardia without peaked T waves. Intravenous 0.9% saline has been started. What is the most appropriate next step in management?
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