3 × 4 Cm in Surgery — 48yo Woman | General Surgery | SMLE Q#1223

SMLE Question #1223

Surgery General Surgery

Objective: OBJ-TRACH-EMERG-01

Last updated: February 2026
A 48-year-old woman has 6 months of weight loss, heat intolerance, and palpitations. Examination shows a diffuse, non-tender goiter without cervical lymphadenopathy or compressive symptoms. Thyroid ultrasound shows an enlarged heterogeneous gland with a 3 × 4 cm right-lobe nodule and a 1 × 2 cm left-lobe nodule, neither with suspicious sonographic features. What is the most appropriate next step in management of her thyroid nodules?

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