Increasing Abdominal Distension in Pediatrics — 7yo Child | Pediatric Gastroenterology | SMLE Q#12133
SMLE Question #12133
Pediatrics
Pediatric Gastroenterology
Objective: OBJ-289
Last updated: February 2026
A 7-year-old boy has 3 months of progressive jaundice, pruritus, fatigue, dark urine, and pale stools with increasing abdominal distension. Examination shows icterus, hepatosplenomegaly, and mild ascites. Viral hepatitis serology is negative. A chronic cholestatic liver disease is suspected, and the clinician needs a test that can confirm the diagnosis and stage hepatic inflammation and fibrosis. What is the gold-standard investigation?
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