6 Months Of Progressive in Medicine / Internal Medicine — 58yo Man | Respiratory / Pulmonology | SMLE Q#12120

SMLE Question #12120

Medicine / Internal Medicine Respiratory / Pulmonology

Objective: OBJ-123

Last updated: February 2026
A 58-year-old man presents to a respiratory clinic with 6 months of progressive exertional dyspnea and chronic cough. He has smoked 10–15 cigarettes daily for 35 years. He denies episodic wheeze, nocturnal symptoms, or variable triggers. He reports an unintentional 4-kg weight loss. Examination shows he is thin with digital clubbing and no signs of heart failure. Chest auscultation reveals reduced breath sounds over the right upper zone without diffuse wheeze. What is the most likely diagnosis?

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