2 Days Of Progressive in Medicine / Internal Medicine — 33yo Woman | Nephrology | SMLE Q#12105

SMLE Question #12105

Medicine / Internal Medicine Nephrology

Objective: OBJ-188

Last updated: February 2026
A 33-year-old woman with systemic sclerosis and previously normal kidney function presents with 2 days of progressive drowsiness and blurred vision. She is confused. Examination shows raised JVP, bilateral pitting edema to the knees, and retinal hemorrhages. She has acute kidney injury with heavy proteinuria and microscopic hematuria. What is the most appropriate immediate management?

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