Mucus in Medicine / Internal Medicine — 25yo Man | Gastroenterology | SMLE Q#12071

SMLE Question #12071

Medicine / Internal Medicine Gastroenterology

Objective: OBJ-433

Last updated: February 2026
A 25-year-old man has 3 months of crampy lower abdominal pain and 6–8 daily episodes of bloody diarrhea with mucus. He reports urgency, tenesmus, and a 5-kg unintentional weight loss. His mother and brother have chronic inflammatory bowel disease. Physical examination shows mild diffuse abdominal tenderness. Digital rectal examination reveals blood-stained stool. Which of the following is the most likely diagnosis?

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