Difficulty Concentrating in Pediatrics — 10yo Child | Pediatric Gastroenterology | SMLE Q#11822

SMLE Question #11822

Pediatrics Pediatric Gastroenterology

Objective: OBJ-289

Last updated: February 2026
A 10-year-old boy has 6 months of progressive jaundice, irritability, and declining school performance with difficulty concentrating and writing. Examination shows jaundice, asterixis, spider angiomas, and mild hepatosplenomegaly. Wilson disease is suspected. Which investigation is the gold standard for confirming this diagnosis?

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