Colonic Adenocarcinoma in Medicine / Internal Medicine — 59yo Man | Cardiology | SMLE Q#11723

SMLE Question #11723

Medicine / Internal Medicine Cardiology

Objective: OBJ-163

Last updated: February 2026
A 59-year-old man with colonic adenocarcinoma and known liver metastases is evaluated on the surgical ward on postoperative day 2 after a right hemicolectomy. He reports progressive shortness of breath and pleuritic chest pain. CT pulmonary angiography confirms an acute pulmonary embolism. There is no active bleeding and the postoperative course has otherwise been uncomplicated. Which of the following is the most appropriate initial anticoagulant therapy?

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