3 Months Of Low in Medicine / Internal Medicine — Case | Endocrinology | SMLE Q#11698
SMLE Question #11698
Medicine / Internal Medicine
Endocrinology
Objective: OBJ-ADDISON-DOSE-1
Last updated: February 2026
A 23-year-old university student presents with 3 months of low mood, anhedonia, social withdrawal, insomnia, and decreased appetite. They have major depressive disorder and have taken their antidepressant inconsistently for several months with poor symptom control. They are considering regular cannabis use for stress. Mental status examination shows depressed mood and restricted affect, without psychotic features or suicidal intent. Before changing treatment, the clinician wants an initial medical evaluation for reversible contributors. What is the most appropriate initial investigation?
Continue in practice mode
Sign in and start a focused practice session to view options, submit your answer, and read the full explanation.