This Malignancy in Obstetrics & Gynecology — 48yo Woman | General Gynecology | SMLE Q#11628

SMLE Question #11628

Obstetrics & Gynecology General Gynecology

Objective: OBJ-ETH-STERIL

Last updated: February 2026
A 48-year-old woman reports several months of postcoital spotting. She has noticed a small ulcerative lesion on the lateral vaginal wall. Speculum examination shows a 2-cm irregular, friable mass on the upper third of the vaginal wall. Biopsy confirms invasive squamous cell carcinoma. She has no history of diethylstilbestrol exposure and her HIV test is negative. Which infectious agent is most strongly associated with this malignancy?

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