Systemic Lupus Erythematosus in Medicine / Internal Medicine — 28yo Man | Rheumatology | SMLE Q#11560
SMLE Question #11560
Medicine / Internal Medicine
Rheumatology
Objective: OBJ-383
Last updated: February 2026
A 28-year-old man with systemic lupus erythematosus for 3 years has 1 month of worsening joint pain with morning stiffness lasting 1 hour despite hydroxychloroquine 400 mg daily. Examination shows synovitis of both wrists and the second proximal interphalangeal joints bilaterally without deformities. There are no features of renal, neurologic, or other major organ involvement. Which agent should be added to best control his inflammatory arthritis?
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