Hematemesis in Medicine / Internal Medicine — 56yo Man | Gastroenterology | SMLE Q#11392
SMLE Question #11392
Medicine / Internal Medicine
Gastroenterology
Objective: OBJ-433
Last updated: February 2026
A 56-year-old man presents with hematemesis and melena. He uses daily aspirin for secondary prevention of ischemic heart disease. After initial resuscitation, upper endoscopy shows a bleeding duodenal ulcer with high-risk stigmata. Endoscopic hemostasis is achieved using combined injection and thermal therapy. He remains clinically stable with no recurrent bleeding. What is the most appropriate proton pump inhibitor regimen to reduce the risk of rebleeding?
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