Smooth Margins in Medicine / Internal Medicine — 25yo Woman | Endocrinology | SMLE Q#11321
SMLE Question #11321
Medicine / Internal Medicine
Endocrinology
Objective: OBJ-ADDISON-DOSE-1
Last updated: February 2026
A 25-year-old woman is evaluated in an outpatient clinic after a 1.8-cm solitary thyroid lesion was found on routine examination. She has no history of head or neck irradiation and no family history of thyroid cancer. She has no symptoms of thyroid dysfunction. Neck ultrasound shows a solid, isoechoic nodule with smooth margins and no suspicious cervical lymph nodes. Ultrasound-guided aspiration cytology is indeterminate (Bethesda category III: atypia of undetermined significance). What is the most appropriate next step in management?
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