No Significant Lymphadenopathy Or in Pediatrics — 6yo Child | Pediatric Heme/Onc | SMLE Q#1122
SMLE Question #1122
Pediatrics
Pediatric Heme/Onc
Last updated: February 2026
A 6-year-old boy has 3 weeks of progressive pallor, fatigue, easy bruising, and increasing abdominal distension. Examination shows marked pallor, scattered ecchymoses, and firm hepatosplenomegaly with no significant lymphadenopathy or bone tenderness. Complete blood count shows pancytopenia. Peripheral smear shows circulating blast cells, and bone marrow examination shows a hypercellular marrow with a high blast proportion. Which of the following is the most likely diagnosis?
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