Fetal Ascites in Obstetrics & Gynecology — Case | General Gynecology | SMLE Q#11205

SMLE Question #11205

Obstetrics & Gynecology General Gynecology

Objective: OBJ-ETH-STERIL

Last updated: February 2026
A 23-year-old primigravida at 28 weeks’ gestation attends a routine antenatal visit. She reports normal fetal movements. Ultrasound shows marked polyhydramnios with fetal ascites and generalized skin edema. Middle cerebral artery Doppler demonstrates increased peak systolic velocity suggestive of fetal anemia. No major structural anomaly is identified on the scan. Which of the following is the most likely underlying cause of this fetal condition?

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