Wide Pulse Pressure in Medicine / Internal Medicine — 27yo Man | Cardiology | SMLE Q#11142

SMLE Question #11142

Medicine / Internal Medicine Cardiology

Objective: OBJ-163

Last updated: February 2026
A 27-year-old man is referred after a murmur was noted on routine examination. He has no chest pain, dyspnoea, palpitations, or syncope. Auscultation in the sitting position, leaning forward at end-expiration, reveals a high-pitched, blowing, early diastolic decrescendo murmur best heard at the left sternal border (third intercostal space). Peripheral pulses are bounding with a wide pulse pressure. What is the most likely diagnosis?

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