Proton Pump Inhibitor Therapy in Surgery — 55yo Man | General Surgery | SMLE Q#11069

SMLE Question #11069

Surgery General Surgery

Objective: OBJ-TRACH-EMERG-01

Last updated: February 2026
A 55-year-old man has 6 weeks of dark, tarry stools and progressive fatigue. He has been treated with proton pump inhibitor therapy for peptic ulcer disease for 3 months. Upper endoscopy shows multiple chronic ulcers confined to the gastric antrum, with no visible mass. He has ongoing/recurrent bleeding despite medical therapy and supportive care. What is the most appropriate definitive management for his peptic ulcer disease?

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