Overlapping Fingers in Pediatrics — Case | General Pediatrics | SMLE Q#10948

SMLE Question #10948

Pediatrics General Pediatrics

Objective: OBJ-377

Last updated: February 2026
A 1-day-old male newborn is evaluated for multiple congenital anomalies. Physical examination shows prominent occiput, low-set ears, clenched hands with overlapping fingers, micrognathia, and rocker-bottom feet. Cardiac auscultation reveals a harsh holosystolic murmur at the lower left sternal border. Echocardiography demonstrates a ventricular septal defect. Chromosomal analysis is pending. What is the most likely diagnosis?

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