Unrepaired Secundum Atrial Septal in Medicine / Internal Medicine — 23yo Woman | Cardiology | SMLE Q#1080

SMLE Question #1080

Medicine / Internal Medicine Cardiology
Last updated: February 2026
A 23-year-old woman with an unrepaired secundum atrial septal defect attends a routine follow-up. She is asymptomatic with no dyspnea, chest pain, or palpitations. Cardiac auscultation reveals a grade 2/6, high-pitched, blowing, early diastolic decrescendo murmur best heard along the left sternal border with the patient leaning forward at end-expiration. S1 and S2 are normal, and there is no opening snap. What is the most likely diagnosis?

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