No Skip Areas in Medicine / Internal Medicine — 28yo Woman | Gastroenterology | SMLE Q#3586
SMLE Question #3586
Medicine / Internal Medicine
Gastroenterology
Last updated: February 2026
A 28-year-old woman has 2 weeks of crampy lower abdominal pain, bloody diarrhea, and tenesmus. Over the past month, she reports low-grade fever and unintentional weight loss. Examination shows mild diffuse lower abdominal tenderness without peritonism. Colonoscopy shows continuous erythematous, friable mucosa beginning at the rectum and extending proximally, with no skip areas. What is the most likely diagnosis?
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