Lower Abdominal Cramps in Medicine / Internal Medicine — 28yo Man | Gastroenterology | SMLE Q#16641

SMLE Question #16641

Medicine / Internal Medicine Gastroenterology

Objective: OBJ-433

Last updated: February 2026
A 28-year-old man has 2 weeks of bloody diarrhea (8–10 times/day) with lower abdominal cramps, urgency, tenesmus, mucus, and 3-kg weight loss. Digital rectal examination shows blood-stained mucus. Stool samples have been sent to exclude infectious causes. Which of the following is the most appropriate investigation to establish the diagnosis?

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