Isoniazid in Medicine / Internal Medicine — 54yo Man | Infectious Diseases | SMLE Q#12304

SMLE Question #12304

Medicine / Internal Medicine Infectious Diseases

Objective: OBJ-349

Last updated: February 2026
A 54-year-old man has hypertension previously controlled on lisinopril 10 mg daily and amlodipine 5 mg daily. He starts treatment for pulmonary tuberculosis with isoniazid, rifampicin, pyrazinamide, and ethambutol. After 2 weeks, he reports headache and dizziness and has persistent elevated blood pressure despite adherence to all medications. What is the most appropriate adjustment to his medications?

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