Markedly Elevated Reticulocyte Count in Pediatrics — 4yo Child | Pediatric Heme/Onc | SMLE Q#3842

SMLE Question #3842

Pediatrics Pediatric Heme/Onc

Objective: OBJ-153

Last updated: February 2026
A 4-year-old boy has several weeks of pallor and easy fatigability. Examination shows mild conjunctival pallor without jaundice, hepatosplenomegaly, or lymphadenopathy. A complete blood count shows microcytic anemia with a markedly elevated reticulocyte count. Peripheral smear shows numerous target cells and occasional nucleated red blood cells. He is hemodynamically stable. What is the most appropriate next step in management?

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